Saying a brand new publication for Acta Materia Medica journal. Icaritin (ICA) is a prenylflavonoid pure product extracted from vegetation of the Epimedium genus. The approval of ICA softgel capsules as a category 1.2 conventional Chinese language medication (TCM) revolutionary drug represents a serious development providing a novel therapeutic method for sufferers with superior hepatocellular carcinoma (HCC).
Class 1.2 TCM revolutionary medication typically denote extracts and formulations derived from single vegetation, animals, minerals, or different substances. ICA displays numerous pharmacological results, encompassing anti-inflammatory, immune-regulatory, anti-oxidation, anti-osteoporosis, anti-depression, and notably anti-cancer properties.
This text presents a complete overview of the molecular mechanisms underlying the anti-cancer properties of ICA, and additional highlights current progress in use of ICA in most cancers analysis, discusses current challenges, and examines potential alternatives for ICA software and additional improvement.
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Journal reference:
Luo, P., et al. (2025). Antineoplastic results of icaritin: molecular mechanisms and functions. Acta Materia Medica. doi.org/10.15212/amm-2024-0035.