From live performance piano to concern reminiscence analysis, researcher bridges mouse-human research

In a brand new interview revealed in Mind Drugs, Dr. Raül Andero Galí reveals how his early ardour for classical piano formed his distinctive strategy to neuroscience analysis. As an ICREA Analysis Professor on the Autonomous College of Barcelona, Dr. Andero Galí leads groundbreaking research that join mouse and human concern responses, doubtlessly revolutionizing therapies for PTSD and anxiousness problems.

The intersection of stress and reminiscence has captured Dr. Andero Galí’s consideration all through his profession.

“All animals face threats all through their lives, triggering satisfactory stress responses important for survival,” he explains within the interview. “Reminiscences form our actuality, and the truth that these aren’t fastened truths, however malleable constructs influenced by feelings fascinates me.”

His laboratory uniquely combines cutting-edge methods, together with in vivo calcium imaging in mice and human concern response research. Present analysis focuses on understanding how the menstrual cycle influences concern reminiscence formation, utilizing subtle strategies to measure intercourse hormones and concern responses in each species.

What makes Dr. Andero Galí’s strategy significantly noteworthy is his dedication to breaking down conventional analysis boundaries.

“We have to remodel how neuroscience analysis is carried out by breaking down the standard boundaries between animal and human research,” he asserts. “By advocating for extra built-in cross-species approaches, we will create a extra complete and translatable understanding of the human mind.”

The laboratory’s concentrate on neuropeptide receptors presents an intriguing avenue for drug growth. In contrast to present medicines that concentrate on receptors all through your entire mind, these receptors are predominantly expressed in emotional areas, doubtlessly providing extra exact therapy choices for fear-based problems.

Dr. Andero Galí’s journey from musician to neuroscientist affords distinctive insights into the inventive pondering needed for scientific innovation. His laboratory atmosphere displays this philosophy, emphasizing mental development and collaborative studying.

“An important factor for me in my laboratory is that it has a wholesome and optimistic atmosphere wherein the completely different members work together and be taught from one another,” he shares.

Latest publications, together with a 2024 Science Advances paper, exhibit the success of this built-in strategy, displaying concordant information between mouse neuronal exercise and human neuroimaging throughout concern responses. These findings increase necessary questions on intercourse variations in concern processing and the potential for extra focused therapeutic approaches.

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Genomic Press